Oral gavage, also known as oral dosing, is a method of administering drugs or other substances to animals, typically rodents such as mice or rats, by delivering the substance directly into the stomach through a tube that is inserted into the animal’s mouth. The oral gavage technique involves restraining the animal, placing a gavage needle…

Continuous infusion is a method of drug administration in which a medication is delivered continuously over an extended period of time, typically through an intravenous (IV) catheter or pump. This differs from intermittent dosing, in which a drug is given at specific intervals. With this method the drug is delivered at a constant rate to…

HER-2 and EGFR (epidermal growth factor receptor) are both types of cell surface receptors that are involved in regulating cell growth, division, and survival. HER-2 (also known as ErbB2) is a member of the HER family of receptors, which also includes HER-1 (EGFR), HER-3, and HER-4. HER-2 is overexpressed in some types of cancer, including…